業績
2000年
| Hitoshi Aizawa, Takashi Kimura, Kazuki Hashimoto, Osamu Yahara, Koihi Okamoto, Kenjiro Kikuchi Basophilic cytoplasmic inclusion in a case of sporadic juvenile amyoprophic lateral sclerosis Journal of the Neurological Science, 176(2): 83-168, 2000.6 |
| Akira Ido, Naoyuki Hasebe, Hironobu Matsuhashi, Kenjiro Kikuchi Coronary sinus occlusion enhances coronary collateral flow and reduces subendocardial ischemia American Journal of Physiology, 280: H1361-1367, 2001 |
| Yoshinobu Ohsaki, Sachie Tanno, Yuka Fujita, Eri Toyoshima, Satoru Fujiuchi, Yutaka Nishigaki, Sakae Ishida, Atsushi Nagase, Naoyuki Miyokawa, Satoshi Hirata, Kenjiro Kikuchi Epidermal growth factor receptor expression correlates with poor prognosis in no-small cell lung cancer patients with p53 overexpression Oncology Reports, 7: 603-607, 2000 |
| Yoshinobu Ohsaki, Hiroshi Morimoto, Shinovu Osanai, Yutaka Nishigaki, Yuji Akiba, Chitomi Hasebe, Satoshi Hirata, Tamio Aburano, Naoyuki Miyokawa, Kenjiro Kikuchi Extensively calcified hemangioma of the diaohragm with increased 99mTc-Hydroxymethylene diphosphonate uptake Internal Medicine, 39(7): 576-578, 2000.7 |
| Yoshinobu Ohsaki, Yutaka Nishigaki, Kaneyoshi Takeyama, Kyoko Nakanishi, Hiroshi Ide, Kakuya Matsumoto, Hiroki Saito, Shinobu Osanai, Kenjiro Kikuchi, Susumu Nakajima Visualization of cancer using high sensitive fluorodynamic camera and fiber-optic endoscope Porphyrins, 9(3.4): 197-203, 2000 |
| AYuji Ogawa, Takashi Haneda, Tomoya Hirayama, Hiroshi Ide, Atsushi Obara, Junichi Maruyama, Hideo Morimoto, Hideichi Tanaka, Junichi Kato, Takuji Hayakawa, Naoyuki Hasebe, Kenjiro Kikuchi Effects of lisinopril and hitrendeipine on urinary albumin excretion and Renal function in patients with mild to moderate essential hypertension Hypertension Research, 23: 607-612, 2000 |
| Charmaine Rozanow, Arijit Roy, Anil Mokashi, Shinobu Osanai, Peter Daudu, Bayard Storey, Sukhamay Lahiri The metabolic hypothesis revisited Oxygen Sensing Molecular to Man, 397-404, 2000 |
| Takayuki Katayama, Yukie Ogura, Hitoshi Aizawa, Hikaru Kuroda, Yasuhiro Suzuki, Kenji Kuroda, Kenjiro Kikuchi Nineteen CAG repeats of the SCA6 gene in a Japanese patient preseting with atacia. Journal of Neurology, 415: 711-712, 2000 |
| Jun-ichi Kawabe, Yoshiaki Aizawa, Naohumi Takehara, Naoyuki Hasebe, Kenjiro Kikushi Glucose modifies the cross-talk between insulin and the adrenergic signaling system in vascular smooth muscle cells Journal of Hypertension, 18: 1457-1464, 2000 |
| Nobuyuki Sato, Hideo Tanaka, Yoshizumi Habuchi, Wayne R. Giles Electrophysiological effects of ibutilide on the delayed rectifier K+ current in rabbit sinoatrial and atrioventricular node cells. European Journal of Pharmacology, 404: 281-288, 2000 |
| Toshiaki Shishido, Kazuko Hayashi, Kenji Shigemi, Takayuki Sato, Masaru Sugimachi, Kenji Sunagawa Single-Beat estimation of End-Systolic elastance using bilinearly approximated Time-Varying Elastance curve Circulation, 102(16): 1983-1989, 2000.10 |
| Kazuko Hayashi, Kenji Shigemi, Toshiaki Shishido, Masaru Sugimachi, Kenji Sunagawa Single-beat estimation of ventriculae end-systolic elastance-effective arterial elastance as an index of ventricular mechanoenergetic performance Anesthesiology, 92(6): 1769-1776, 2000.6 |
| Fumihiko Takahashi, Yuji Ogawa, Naoyuki Hasebe, Syunsuke Natori, Yoshihiko Tokasashi, Naoyuki Miyokawa, Kenjiro Kikuchi Successful treatment of a patient with nephritic syndrome associated with chronic lymphocytic leukemia Internal Medicine, 39(3): 256-259, 2000.3 |
| Naohumi Taklehara, Jun-ichi Kawabem Yoshiaki Aizawa, Naoyuki Hasebe, Kenjiro Kikuchi High glucose attenuates insulin-induced mitogen-activated protein kinase phosphatase-1 (MKP-1) expression in vascular smooth muscle cells. Biochimica et Biophysica Acta, 1497: 244-252, 2000 |
| S.D.Lee, Hitoshi Nakano, L.E.Gosselin, J.A.Krasney, E.H.Schlenker, G.A.Farlas Endogenous opiods modulate ventilation and peak oxygen consumption in obese zucker rats. Am J Pespir Crit Care Med, 162: 1009-1015, 2000 |
| B.Bishop, G.Silva, J.Ktrasney, A.Salloum, A.Roberts, Hitoshi Nakano, D.Shucard, D.Rifkin, G.Farkas Circadian rhythms of body temperature and activity levels during 63h of hypoxia in the rat. Am J Physiol Regulatory Integrative Comp Ohysiol, 279: R1378-R1385, 2000 |
| Hitoshi Nakano, Hiroshi Ide, Masanobu Omada, Shinobu Osanai, Toru Takahashi, Kenjiro Kikuchi, Jun Iwamoto Reduce nasal nitric oxide in diffuse panbronchiolitis Am J Respir Crit Care Med,162: 2218-2220, 2000 |
| Yasuhiro Nakamura, Takashi Haneda, Junzo Osaki, Setsuya Miyata, Kenjiro Kikuchi Hypertrophic growth of cultured neonatal rat heart cells mediated by vasopressin V1A receptor European Journal of Pharmacology, 391: 39-48, 2000 |
| Shunsuke Natori, Naoyuki Hasebe, Yin-Tie Jin, Tomoyuki Matsusaka, Takafumi Ohta, Shiro Tsuji, Masahiko Morihira, Hideki Nakamura, AkiraIdo, Hironobu Matsuhashi, Kenjiro Kikuchi Effect of inhaled nitric oxide on cardiovascular response to catecholamine in heart failure. Journal of Cardiovascular Pharmacology, 36(Suppl 2): S55-S60, 2000 |
| Takashi Haneda, Yuji Ogawa, Junichi Kato, Hironobu Matsuhashi, Hideo Morimoto, Hajime Honda, Takashi Takenaka, Satoshi Tanazawa, Ryo Kataoka, Kenjiro Kikuchi Effect of celiprolol on cardiac hypertrophy in hypertension Hypertension Research, 23: 467-474, 2000 |
| Naohumi Taklehara, Jun-ichi Kawabem Yoshiaki Aizawa, Naoyuki Hasebe, Kenjiro Kikuchi High glucose attenuates insulin-induced mitogen-activated protein kinase phosphatase-1 (MKP-1) expression in vascular smooth muscle cells. Biochimica et Biophysica Acta, 1497: 244-252, 2000 |
| Jyun Fukuzawa, George W Booz, Rachel A.Hunt, Noriko Shimizu, Vijaya Karoor, Kenneth M.Baler, David E.Dostal Cardiotrophin increases angiotensinogen mRNA in rat cardiac myocytes through STAT3 an autocrine loop for hypertrophy Hypertension, 35: 1191-1196, 2000.6 |
| Takayuki Fujino, Masaaki Fujita, Takafumi Ohta, Takayuki Harada, Jyunichi Kato, Naoyuki Hasebe, Kenjiro Kikuchi Relationship between serum lipoprotein (a) level and thrombin generation to the circadian variation in onset of acute myocardial infarction Atherosclerosis, 155: 171-178, 2000 |
2001年
| Zhao C, Shuke N, Yamamoto W, Okizaki A, Sato J, Ishikawa Y, Ohta T, Hasebe N, Kikuchi K, Aburano T Comparison of cardiac sympathetic nervous function with left ventricular function and perfusion in cardiomyopathies by 123I-MIBG SPECT and 99mTc-Tetrofosmin electrocardiographically gated SPECT Journal of Nuclear Medicine, 42(7): 1018-1024, 2001 |
| Ido A, Hasebe N, Matsuhashi H, Kikuchi K Coronary sinus occlusion enhaces coronary collateral flow and reduced subendocardial ischemia Am J Physiol (Heart Circ Physiol), 280: H1361-H1367, 2001 |
| Obata H, Mitsuoka T, Kikuchi Y, Sakurada T, Kusajima K, Kawamura Y, Kikuchi K Twenty-Seven-Year follow-up of arrhymogenic right ventricular dysplasia PACE, 24(Pt.1): 510-511, 2001 |
| Fujino T, Kato J, Fujita M, Ohta T, Harada T, Hasebe N, Kikuchi K Relationship between serum lipoprotein (a) level and thrombin generation to the circadian variation in onset of acute myocardial infarction Atherosclerosis, 155: 171-178, 2001 |
| Tanabe Y, Inagaki M, Kurita T, Nagaya N, Taguchi A, Suyama K, Aihara N, Kamakura S, Sunagawa K, Nakamura K, Ohe T, Towbin J A, Priori S G, Shimizu W Sympathetic stimulation produces a greater increase in both transmural and spatial dispersion of repolarization in LQT1 than LQT2 forms of congenital long QT syndrome Journal of the American College of Cardiology, 37(3): 911-919, 2001 |
| Ito T, Kikuchi K, Odagawa Y, Takata S, Yano K, Okada S. Haneda N, Ogawa S, Nakano O, Kawahara Y, Kasai H, Nakayama T, Hukutomi T. Sakurada H, Shimizu A, Yazaki Y,Nagai R, Nakamura Y, Tanaka T Correlation of genetic etiology with response to _-adrenergic blockade among symptomatic patients with familial long-QT syndrome J Hum Genet, 46: 38-40, 2001 |
| Yamamoto W, Shuke N, Usui K, Aburano T, Takehara N, Kikuchi K Intense uptake of technetium-99m tetrofosmin by lactating breasts Clinical Nuclear Medicine, 26: 76-77, 2001 |
| Nakai S, Shinzato T, Sanaka T, Kikuchi K, Kitaoka T, Shinoda T, Yamazaki C, Sakai R, Omori H, Morita O, Iseki K, Kubo K, Tabei K, Masakane I, Fushimi K, Akiba T An overview of dialysis treatment in japan (as of Dec.31, 1999) Journal of Japanese Society for Dialysis Therapy, 34(7): 1121-1147, 2001 |
| Aizawa Y, Kawabe J, Hasebe N, Takehara N, Kikuchi K Pioglitazone enhances cytokine-induced apoptosis in vascular smooth muscle cells and reduces intimal hyperplasia Circulation, 104: 455-460, 2001 |
| Toyoshima E, Ohsaki Y, Nishigaki Y, Fujimoto Y, Kohgo Y, Kikuchi K Expression of syndecan-1 is common in human lung cancer independent of expression of epidermal growth factor receptor Lung Cancer. 31: 193-202, 2001 |
| Osanai S, Takahashi T, Enomoto H, Satoh N, Yahara O, Akiba Y, Fujiuchi S, Nakano H, Ohsaki Y, Kikuchi K Hypoxic ventilatory depression in a patient with mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes Respirology, 6: 163-166, 2001 |
| Ogasa T, Nakano H, Ide H, Yamamoto Y, Sasaki N, Osanai S, Akiba Y, Kikuchi K, Iwamoto J Flow-mediated release of nitric oxide in isolated, perfused rabbit lungs J Appl Physiol, 91: 363-370, 2001 |
| Nakano H, Lee S D, Ray A D, Krasne J A, Farkas G A Role of nitric oxide in thermoregulation and hypoxic ventilatory response in obese Zucker rats Am J Respir Crit Care Med, 164: 437-442, 2001 |
| Nakano H, Magalang U J, Lee S D, Krasney J A, Farkas G A Serotonergic modulation of ventilation and upper airway stability in obese Zucker rats Am J Repir Crit Care Med, 163: 1191-1197, 2001 |
| Lee S D, Nakano H, Farkas G A GABAergic modulation of ventilation and peak oxygen consumption in obese Zucker rats J Appl Physiol, 90: 1707-1713, 2001 |
| Bishop B, Silva G, Krasney J, Nakano H, Roberts A, Farkas G, Riflin D, Shucard D Ambient temperature modulation hypoxic-induced changes in rat body temperature and activity differentially Am J Physiol Regulatory Integrative Comp Physiol, 280: R1190-R1196, 2001 |
| Yamamoto Y, Nakano H, Ide H, Ogasa T, Takahashi T, Osanai S, Kikuchi K, Iwamoto J Role of airway nitric oxide on the regulation of pulmonary circulation by carbon dioxide J Appl Physiol, 91: 1121-1130, 2001 |
| Naofumi Takehara, Yuichiro Kawamura, Nobuyuki Sato, Aki Sato, Hiroyuki Kakuchi, Kenjiro Kikuchi A case of familial atrioventricular heart block affected by alteration of the autonomic nervous system Journal of Electrocardiology, 34(4): 339-344, 2001 |
| Koichi Okamoto, Yukio Fujita, Hitoshi Aizawa, Hirohumi Kusaka, Ban Mihara Basophilic cytoplasmic inclusions in amyotrophic lateral scleeosis Molecular Mechanism and Therapeutic of Amyotrophic Lateral Sclerosis, 21-26, 2001 |
| Ukihide Tateishi, Satoshi Terae, Akihiko Ogata, Yutaka Sawamura, Yasuhiro Suzuki, Satoru Abe, Kazuo Miyasaka MR imaging of the brain in lymphomatoid granulomatosis Am J Neuriradiol, 22: 1283-1290, 2001 |
| Sachie Tanno, Yoshino u Ohsaki, Shinobu Osanai, Yuji Akiba, Toshiharu Takeuchi, Yutaka Nishigaki, Hiroshi Ide, Hitoshi Nakano, Naoyuki Miyokawa, Kejiro Kikuchi Spontaneous rupture of the amyloid spleen in a case of usual interstitial pneumonia Internal Medicine, 40(5): 428-431, 2001 |
| Takayuki Katayama, Hitoshi Aizawa, Kenji Kuroda, Yasuhiro Suzuki, Kenjiro Kikuchi, Takashi Kimura, Kazuki Hashimoto, Osamu Yahara Cortical silent period in the tongue induced by transcranial magnetic stimulation Journal of the Neurological Sciences, 193: 37-41, 2001 |
| Takafumi Ohta, Naoyuki Hasebe, Shiro Tsuji, Yin-Tie Jin, Shinsuke Kido, Shunsuke Natori, Motohiko Sato and Kenjiro Kikuchi Effects of angiotensin converting enzyme inhibitor and angiotensin _ type 1 receptor blocker on cardiac dysfunction induced by isoproterenol in dogs Journal of Cardiovascular Pharmacology, 38(suppl.1): S63-S67, 2001 |
| Guidelines for the management of hypertension for general practitioners Japanese Society of Hypertension Guidelines Subcommittee for the Management of Hypertension Kenjiro Kikuchi, et al Hypertension Research, 24(6): 613-634, 2001 |
| Satoshi Koyama, Hitoshi Aizawa, Kazutoyo Morita, Toshiaki Fujikane, Nobuhiro Sasaki, Kenjiro Kikuchi Plasma von willebrand factor activities in vascular parkinsonism: comparison with parkinson's disease Journal of Stroke and Cerebrovascular Diseases. 10(5): 227-230, 2001 |
2002年
| Hitoshi Nakano, Shin-Da Lee, and Graspar A. Farkas Dopaminergic modulation of ventilation in obese Zucker rats J Appl Physiol, 92: 25-32, 2002 |
| K.Noda, Y. Nishiwaki, M. Kawahara, S. Negoro, T. Sugiura, A. Yokoyama, Ｍ. Fukuoka, K. Mori, K. Watanabe, T. Tamura, S. Yamamoto, N. Saijo, for the Japan Clinical Oncology Gyoup. Y. Ohsaki appears as a principle investigator. Irinotecan plus cisplatin compared with etoposide plus cisplatin for extensive small-cell lung cancer N Engl J Med, 346(2): 85-91, 2002 |
| Hajime Honda, Kunio Tanaka, Nobuyuki Akita, Takashi Haneda Cyclical changes in High-Energy phosphates during the cardiac cycle Pacing-Gate 31p nuclear magnetic resonance Circulation Journal, 66(1): 80-86, 2002 |
| Kan Morimoto, Takashi Haneda, Kiyotaka Okamoto, Hironori Ishida, Kenjiro Kikuchi Methylenetetrahydrofolate reductase gene polymorphism, hyperhomocysteinemia, and cardiovascular diseases in chronic hemodialysis patients Nephron, 90: 43-50, 2002 |
| Yukio Fujita, Koichi Okamoto, Atsushi Sakurai, Hirofumi Kusaka, Hitoshi Aizawa, Ban Mihara, Nicholas K. Gonatas The Golgi apparatus is fragmented in spinal cord motor neurons of amyotrophic lateral sclerosis with basophilic inclusions Acta Neuropathol, 103: 243-247, 2002 |
| Takahiro Shiokoshi, Yoshinobu Ohsaki, Junichi Kawabe, Takayuki Fujino and Kenjiro Kikuchi Downregulation of nitric oxide accumulation by cyclooxygenase-2 induction and thromboxane A2 production in interleukin-1_-stimulated rat aortic smooth muscle cells Journal of Hypertension, 20: 455-461, 2002 |
| H Aizawa, N, Makiguchi, T Katayama, S Koyama, K Kikuchi Cherio-oral syndrome due to a midbrain lesion Neurology: 1414, 2002.5 |
| Naoyuki Hasebe, Shinsuke Kido, Akira Ido, Kenjiro Kikuchi Reverse J-Curve relation between diastolic blood pressure and severity of coronary artery lesion in hypertensive patients with angina pectoris Hypertension Research, 25(3): 381-387, 2002 |
| Satoshi Koyama, Hitoshi Aizawa, Tomoaki Haga, Setsu Nakatani-Enomoto, Kenjiro Kikuchi An autopsy case of amyotrophic lateral sclerosis accompanied by syndrome of inappropriate secretion of antidiuretic hormone Internal Medicine, 41(5): 395-397, 2002 |
| Hitoshi Nakano, Hiroshi Ide, Toshiyuki Ogasa, Shinobu Osanai, Masanobu Imada, Satoshi Nonaka, Kenjiro Kikuchi, Jun Iwamoto Ambient oxygen regulates epithelial metabolism and nitric oxide production in the human nose J Appl Physiol, 93: 189-194, 2002 |
| Satoshi Koyama, Nobuyuki Sato, Kimimoto Nagashima, Hitoshi Aizawa, Yuichiro Kawamura, Naoyuki Hasebe, Hiroshi Iwaki, Kenjiro Kikuchi Effects of right stellate ganglion block on the autonomic nervous function of the heart - A study using the head-up tilt test- Circulation Journal, 66(7): 645-648, 2002 |
| Takayuki Fujino, Koh-ichi Yuhki, Takehiro Yamada, Akyoshi Hara, Osamu Takahata, Yuji Okada, Chun-Yang Xiao, Hong Ma, Hideji Karibe, Yasunori Iwashima, Jun Fukuzawa, Naoyuki Hasebe, Kenjiro Kikuchi, Shuh Nayumiya and Fumitaka Ushikubi Effect of the prostanoids on the proliferation or hypertrophy of cultured murine aortic smooth muscle cells British Journal of Pharmacology, 136: 530-539, 2002 |
| Jun Fukuzawa, Jun Nishihara, Naoyuki Hasebe, Takashi Haneda, Junzo Osaki, Tetsuya Saito, Tomoaki Nomura, Takayuki Fujino, Nobutaka Wakamiya, Kenjiro Kikuchi Contribution of macrophage migration inhibitory factor to extracellular signal-regulated kinase activation by oxidative stress in cardiomyocytes Journal of Biological Chemistry, 277(28): 24889-24895, 2002 |
| Shigeru Nakai, Takahiro Shinzato, Tsutomu Sanaka, Kenjiro Kikuchi, Takeki Kitaoka, Toshio Shinoda, Chikao Yamazaki, Rumi Sakai, Hiroyuki Omori, Osamu Morita, Kunitoshi Iseki, Kazuo Kubo, Kaoru Tabei, Ikuto Masakane, Kiyohide Fushimi, Atsushi Wada, Naoko Miwa, Takashi Akiba The current state of chronic dialysis treatment in Japan (as of December 31, 2001) Journal of Japanese Society for Dialysis Therapy, 35(7): 1155-1184, 2002 |
| Y. Ohsaki, K. Takeyama, S. Nakao, S. Tanno, E. Toyoshima, K. Nakanishi, Y. Nishigaki, T. Ogasa, S. Osanai, K. Kikuchi, S. Nakajima Detection of photofrin full-color endscopic fluorescence imaging system: A preliminary report. Diagnostic Therapeutic Endoscopy, 7: 187-195, 2002 |
| S. Hosoe, K. Komuta, K. Shibata, H. Harada, Y. Iwamoto, Y. Ohsaki, T. Morita, H. Origasa, M. Fukushima, K. Furuse, M. Kawahara Gemicitabine and vinorelbine followed by docetaxel in patients with advanced non-small cell lung cancer: A multi-international phase _ trial of non-platinum sequential triplet combination chemotherapy (JMTO LC00-02) Br J Cancer in press, 2002 |
2003年
| Takeuchi T, Sato N, Kawamura Y, Takahashi F, Sato M, Kikuchi K, Akasaka N, Go K, Huzimoto K, Hasebe N A case of a short-coupled variant of torsades de pointes with electrical storm PACE 26(2): 632-6, 2003 |
| Hosoe S, Komuta K, Shibata K, Harada H, Iwamoto Y, Oosaki Y, Morioka T, Origasa H, Fukushima M, Furusem K, Kawahara M Gemcitabine and vinorelbine followed by docetaxel in patients with advanced non-small-cell lung cancer: a mult-institutional phaseII trial of nonplatinum sequential triplet combination chemotherapy (JMTO LC00-2) British Journal of Cancer 88(3): 342-347, 2003 |
| Ido A, Hasebe N, Takeuchi T, Kikuchi K Effects of temocapril olmesartan on myocardial sympathetic nervous activity and fatty acid metabolism in rats with chronic β?adrenergic stimulation Journal of Cardiovascular PharmacologyTM 41(Suppl.1): S133-S137, 2003 |
| Kawahara Y, Shin Kwak, Hui Sun, Ito K, Hashida H, Aizawa H, Seon-Yong Jeong, Kanazawa I Human spinal motoneurons express low relative abundance of GluR2 mRNA: an implication for excitotoxicity in ALS Journal of Neurochemistry 85: 680-689, 2003 |
| Myojo M, Fujiuchi S, Matsumoto H, Yamazaki Y, Takahashi M, Satoh K, Takeda A, Nishigaki Y, Okamoto K, Fujita Y, Fujikane Y, Shimizu T Disseminated Mycobacterrium avium complex(DMAC) in an immunocompetent adult INT J TUBERC LUNG DIS 7(5): 498-501, 2003 |
| Sekine I, Nishiwaki Y, Noda K, Kudoh S, Fukuoka M, Mori K, Negoro S, Yokoyama A, Matsui K ,Ohsaki Y ,Nakano T, Saijo N Randomized phase Ⅱ study of cisplatin,irinotecan and etoposide combinations administered weekly or every 4 weeks for extensive small-cell lung cancer(JCOG9902-D1) Annuals of Oncology 14: 709-714, 2003 |
| Uekita K, Hasebe N, Funayama N, Aoyama H, Kuroda K, Aizawa H, Kataoka R, Kikuchi K Cervical and Intracranial Atherosclerosis and Silent Brain Infarction in Japanese Patients with Coronary Artery Disease Cerebrovasc Dis 16: 61-68, 2003 |
| Fujino T, Hasebe N, Kawabe J, Fujita M, Fukuzawa J, Tobise K, Kikuchi K Effect of B-adrenoceptor antagonist and angiotensin-converting enzyme inhibitor on hypertension-associated changes in adeylyl cyclase type V messenger RNA expression in spontaneously hypertensive rats J Cardiovasc Pharmacol 41(5): 720-725, 2003 |
| Nishigaki Y, Fujiuchi S, Yamazaki Y, Matsumoto H, Takeda A, Fujita Y, Okamoto K, Fujikane T, Shimizu T, Kikuchi K Increased vascular endothelial growth in acute eosinophilic pneumonia Eur Respir J 21: 774-778, 2003 |
| Natori S, Hasebe N, Yin-Tie Jin, Matsusaka T, Ido A, Matsuhashi H, Ihara T, Kikuchi K Inhaled nitric oxide modifies left ventricular diastolic stress in the presence of vasoactive agents in heart failure American Journal of Respiratory and Critical Care Medicine 167: 895-900, 2003 |
| Suzuki Y, Nakagami S, Namikawa K, Sumiko Kiryu-Seo, Inagaki N, Kaibuchi K, Aizawa H, Kikuchi K, Kiyama H Collapsing response mediator protein-2 accelerates axon regeneration of nerve-injured motor neurons of rat. Journal of Neurochemistry 86(4): 1042-50, 2003 |
| Nakagomi S, Suzuki Y, Namikawa K, Sumiko Kiryu-Seo, Kiyama H Expression of the Activating Transcription Factor3 Prevents c-Jun N-Terminal Kinase-Induced Neuronal Death by Promoting Heat Shock Protein 27 Expression and Akt Activation. The Journal of Neuroscience 23(12): 5187-96, 2003 |
| Ohsaki Y, Tachibana M, Nakanishi K, Nakao S, Saito K, Toyoshima E, Sato M, Takahashi T, Osanai S, Itoh Y, Kikuchi K Alterations in penicillin binding protein gene of Streptococcus pneumoniae and their correlation with susceptibility patterns International Journal of Antimicrobial Agents 22(2): 140-6, 2003 |
| Fujino T, Ishii Y, Takeuchi T, Hirasawa K, Tateda K, Kikuchi K, Hasebe N Recovery of BMIPP uptake and regional wall motioned insulin resistant patients following angioplasty for acute myocardial infarction. Circulation Journal 67(9): 757-762, 2003 |
| Saito T, Fukuzawa J, Osaki J, Sakuragi H, Yao N, Haneda T, Fujino T, Wakamiya N, Kikuchi K, Hasebe N Roles of calcineurin and calcium／calmodulin-dependent protein kinase Ⅱ in pressure overload-induced cardiac hypertrophy Journal Molecular and Cellular Cardiology 35: 1153-1160, 2003 |
| Yamada T, Fuzino T, Yuhki K, Hara A, Karibe H, Takathata O, Okada Y, Chun-Yang Xiao, Takayama K, Kuriyama S, Taniguchi T, Shiokoshi T, Ohsaki Y, Kikuchi K, Narumiya S, Ushikubi F Thromboxane A2 regulates vascular tone via its inhibitory effect on the expression of inducible nitric oxide synthase Circulation 108: 2381-86, 2003 |
| Appendix: Kikuchi K Naikatani S, Mitsutake K, Hozumi T, Yoshikawa J, Akiyama M, Yoshida K, Ishizuka N, Nakamura K, Tanigucni Y, Yoshioka K, Kawazoe K, Akaishi M, Niwa K, Nakazawa M, Kitamura S, Miyatake K, Committee on Guideline for Prevention and Management of Infective Endocarditis, Japanese Circulation Society Current Characteristics of Infective Endocarditis in Japan-An Analysis of 848 Cases in 2000 and 2001- Circulation Journal 67(11): 901-905, 2003 |
| Chunlei Zhao, Shuke N, Okizaki A, Yamamoto W, Sato J, Ishikawa Y, Ohta T, Hasebe N, Kikuchi K, Aburano T Comparison of myocardial fatty acid metabolism with left ventricular function and perfusion in cardiomyopathies :by 123I-BMIPP SPECT and 99mTc-tetrofosmin electrocardiographically gated SPECT Nuclear Medicine 17(7): 541-548, 2003 |
| Okizaki A, Shuke N, Sato J, Ishikawa Y, Yamamoto W, Kikuchi K, Amurano T Improved accuracy in estimation of left ventricular function parameters from QGS software with Tc-99m tetrofosmin gated-SPECT:a multivariate analysis Nuclear Medicine 17(7): 575-582, 2003 |
| Fujiuchi S, Matsumoto H, Yamazaki Y, Nakata H, Takahashi M, Nakao S, Takeda A, Okamoto K, Fujita Y, Fujikane T, Shimizu T Impaired interleukin-1β converting enzyme(ICE)activity in patients with pulmonary tuberculosis INT J TUBERC LUNG DIS 7(11): 1109-1112, 2003 |
| Hirata S, Saito T, Kiyanagi K, Kitada M, Yamazaki K, Sasazima T, Ohsaki Y, Miyakawa N Granulomatous mastitis diagnosed by core-needle biopsy and successfully treated with corticosteroid therapy: A case report Breast Cancer 10(4): 378-381, 2003 |
| Itoh T, Aizawa H, Hashimoto K, Yoshida K, Kimura T, Katayama T, Koyama S, Yahara O, Kikuchi K Corrigendum to “Prevalence of multiple sclerosis in Asahikawa, a city in northen Japan” Journal of the Neurological Sciences 214(1-2): 7-9, 2003 |
| Takahashi F, Hasebe N, Chinda J, Okada M, Takeuchi T, Hirayama T, Imamoto C, Kikuchi K A case of nephrotic syndrome associated with renovascular hypertension successfully treated with candesartan. Hypertens Res, 26(1): 123-127, 2003 |
| Nakagawa N, Osanai S, Ide H, Nishigaki Y, Takahashi S, Nakano H, Ohsaki Y, Kikuchi K, Tokusashi Y and Obata H Severe Pulmonary Hypertension Associated with Primary Sjogren's Syndrome. Internal Medicine 42：1248-1252, 2003 |
| Fujita Y, Fujikane T, Fujiuchi S, Nishigaki Y, Yamazaki Y, Nagase A, Shimizu T, Ohsaki Y, Kikuchi K The diagnostic and prognostic relevance of human telomerase reverse transcriptase mRNA expression detected in situ in patients with nonsmall cell lung carcinoma Cancer 98(5): 1008-1013, 2003 |
| Takahashi T, Osanai S, Nakano H, Ohsaki Y, Kikuchi K Doxapram stimulates carotid body with different mechanisms from hypoxic chemotransduction Adv Exp Med Biol 536: 129-134, 2003 |
| Osanai S, Takahashi T, Nakano H, Ohsaki Y, Kikuchi K Effect of HERG-like potassium channel blocker on the carotid body chemoreception Adv Exp Med Biol 536: 117-122, 2003 |
2004年
| Nakatani-Enomoto S, Aizawa H, Koyama S, Kuroda K, Kimura T, Kikuchi K. Transient swelling of peripheral nerves in a case of neurosarcoidosis Intern Med. 43: 1078-81, 200 |
| Tanno S, Ohsaki Y, Nakanishi K, Toyoshima E, Kikuchi K. Small cell lung cancer cells express EGFR and tyrosine phosphorylation of EGFR is inhibited by gefitinib ("Iressa", ZD1839). Oncol Rep. 12: 1053-7, 2004 |
| Fujino T, Nakagawa N, Yuhki K, Hara A, Yamada T, Takayama K, Kuriyama S, Hosoki Y, Takahata O, Taniguchi T, Fukuzawa J, Hasebe N, Kikuchi K, Narumiya S, Ushikubi F. Decreased susceptibility to renovascular hypertension in mice lacking the prostaglandin I2 receptor IP J Clin Invest. 114: 805-12, 2004 |
| Tanno S, Ohsaki Y, Nakanishi K, Toyoshima E, Kikuchi K. Human small cell lung cancer cells express functional VEGF receptors, VEGFR-2 and VEGFR-3 Lung Cancer 46: 11-9, 2004 |
| Ohta T, Hasebe N, Tsuji S, Izawa K, Jin YT, Kido S, Natori S, Sato M, Kikuchi K. Unequal effects of renin-angiotensin system inhibitors in acute cardiac dysfunction induced by isoproterenol. Am J Physiol Heart Circ Physiol. 287: H2914-21, 2004 |
| Okada M, Hasebe N, Aizawa Y, Izawa K, Kawabe J, Kikuchi K. Thermal treatment attenuates neointimal thickening with enhanced expression of heat-shock protein 72 and suppression of oxidative stress. Circulation. 109: 1763-8, 2004 |
| Fujikane T, Fujiuchi S, Yamazaki Y, Matsumoto H, Takahashi M, Fujita Y, Shimizu T, Kikuchi K. Molecular epidemiology of tuberculosis in the north Hokkaido district of Japan Int J Tuberc Lung Dis. 8: 39-44, 2004 |
| Takehara N, Makita N, Kawabe J, Sato N, Kawamura Y, Kitabatake A, Kikuchi K. A cardiac sodium channel mutation identified in Brugada syndrome associated with atrial standstill. J Intern Med. 255: 137-42, 2004 |
| Kawahara Y, Ito K, Hui Sun, Aizawa H, Kanazawa I, Shin Kwak RNA editing and death of motor neurons NATURE, 427: 801, 2004 |
| Itoh T, Aizawa H, Hashimoto K, Kimura T, Katayama T, Koyama S, Yahara O, Kikuchi K Corrigenbum to "Prevalence of multiple sclerosis in Asahikawa, a city in northern Japan" J Neurological Sci, 217: 115, 2004 |
| Chunlei Zhao, Shuke N, Okizaki A, Ymamamoto W, Usui K, Kikuchi K, Kaneko S, Yachiku S, Sasajima T, Aburano T Optimization of the uptake method for estimationg renal clearance of 99mTC mercaptoacetyleriglycine Nuclear MedicineCommunications 25: 159-166, 2004 |
| The Japanese β-blockers and Calcium Antagonists Myocardial Infaction (JBCMI) Investigators Comparison of the effects of beta blockers and calcium antagonists of cardiovascular events after acute myocardial infarction in Japanese subjects. Am J Cardiol, 93: 969-973, 2004 |
| Maeda M, Ohba N, Nakagomi S, Suzuki Y, Kiryu-Seo, S, Namikawa K, Kodoh W, Tanaka A, Kiyama H Vesicular acetylcholine transporter can be a morphological marker for the reinnervation to muscle of regenerating motor axons. Neuroscience Research 48: 305-314, 2004 |
| Ichinose Y, Nakai Y, Kudoh S, Semba H, Yoshida S, Nukiwa T, Yamamoto H, Yamane Y, Nitani H, and UP-RT Study Group APPENDIX：Ohsaki Y Urascil/Tegafur Plus Cisplatin with Concurrent Radiotherapy for Locally Advanced Non-Small-Cell Lung Cancer：A Multi-institutional PhaseⅡTrial. Clinical Cancer Research 10: 4369-73, 2004 |
2005年
| Fujikawa K, Hasebe N, Kikuchi K; NICE-Combi Study Group Cost-effectiveness analysis of hypertension treatment: controlled release nifedipine and candesartan low-dose combination therapy in patients with essential hypertension--the Nifedipine and Candesartan Combination (NICE-Combi) Study. Hypertens Res. 28(7):585-91, 2005 |
| Takahashi F, Hasebe N, Kawashima E, Takehara N, Aizawa Y, Akasaka K, Kawamura Y, Kikuchi K Hyperinsulinemia is an independent predictor for complex atherosclerotic lesion of thoracic aorta in non-diabetic patients. Atherosclerosis, 2005 Oct 5; [Epub ahead of print] |
| Ogura Y, Kato J, Ogawa Y, Shiokoshi T, Kitaoka T, Suzuki T, Kawamura Y, Tanabe Y, Sato N, Hasebe N, Kikuchi K A case of alternating bundle branch block in combination with intra-hisian block. Int Heart J 46(4): 737-44, 2005 |
| Takehara N, Hasebe N, Enomoto S, Takeuchi T, Takahashi F, Ota T, Kawamura Y, Kikuchi K Multiple and recurrent systemic thrombotic events associated with congenital anomaly of inferior vena cava. J Thromb Thrombolysis 19(2):101-3, 2005 |
| Zhao C, Shuke N, Okizaki A, Yamamoto W, Sato J, Iwata K, Kanno T, Hasebe N, Kikuchi K, Aburano T Naturally formed coronary arterial thrombus detected by In-111 oxine platelet imaging. Clin Nucl Med 30(7): 492-5, 2005 |
| Takahashi F, Hasebe N, Ogawa Y, Tsuji S, Kido S, Aburano T, Kikuchi K Renal artery stenosis emerged after angiotensin-converting enzyme inhibitor treatment for myocardial infarction: a case report. Angiology 56(3): 347-50, 2005 |
| Takahashi T, Osanai S, Nakano H, Ohsaki Y, Kikuchi K Doxapram stimulates the carotid body via a different mechanism than hypoxic chemotransduction. Respir Physiol Neurobiol 147(1): 1-9, 2005 |
| Osanai S, Takahashi T, Nakano H, Kikuchi K Doxapram inhibits carotid sinus baroreceptors in rabbits. Auton Autacoid Pharmacol 25(2): 79-84, 2005 |
| Hasebe N, Kikuchi K; NICE Combi Study Group Controlled-release nifedipine and candesartan low-dose combination therapy in patients with essential hypertension: the NICE Combi (Nifedipine and Candesartan Combination) Study. J Hypertens 23(2): 445-53, 2005 |
2006年
| Morihira M, Hasebe N, Erdene B, Sumitomo K, Matsusaka T, Izawa K, Fujino T, Fukuzawa J, Kikuchi K Ischemic Preconditioning Enhances Scavenging Activity of Reactive Oxygen Species and Diminishes Transmural Difference of Infarct Size. Am J Physiol Heart Circ Physiol 290(2): H577-583, 2006 |
| Kido S, Hasebe N, Ishii Y, Kikuchi K Tachycardia-induced myocardial ischemia and diastolic dysfunction potentiate secretion of ANP, not BNP in hypertrophic cardiomyopathy. Am J Physiol Heart Circ Physiol, 290(3): H1064-1070, 2006 |
| Kawabe J, Okumura S, Mark A.Nathanson, Hasebe N, Ishikawa Y Caveolin regulates microtubule polymerization in the vascular smooth muscle cells Biochem Biophys Res Commun 342(1): 164-169, 2006 |
| Aizawa H, Makita Y, Sumitomo K, Aburakawa Y, Katayama T, Nakatani-Enomoto S, Suzuki Y, Fujiwara K, Enomoto H, Kuroda K, Kimura T, Yahara O, Koyama S, Maruyama J, Nakamura M, Hasebe N, Kikuchi K Edaravone diminishes free radicals from circulating neutrophils in patients with ischemic brain attack. Intern Med 45(1): 1-4, 2006 |
| Nishigaki Y, Fujiuchi S, Fujita Y, Yamazaki Y, Sato M, Yamamoto Y, Takeda A, Fujikane T, Shimizu T, Kikuchi K Increased serum level of vascular endothelial growth factor in Mycobacterium avium complex infection Respirology. 11(4): 407-13, 2006 |
| Takahashi T, Osanai S, Nakao S, Takahashi M, Nakano H, Ohsaki Y, Kikuchi K Stimulus interaction between hypoxia and hypercapnia in the human peripheral chemoreceptors Adv Exp Med Biol 580: 263-6, 2006 |
| Osanai S, Takahashi T, Nakao S, Takahashi M, Nakano H, Kikuchi K Peripheral chemoreceptor activity on exercise-induced hyperpnea in human. Adv Exp Med Biol. 580: 251-5, 2006 |
| Fujiuchi S, Yamazaki Y, Fujita Y, Nishigaki Y, Takeda A, Yamamoto Y, Fujikane T, Shimizu T, Osanai S, Takahashi T, Kikuxhi K S-nitrosoglutathione (SNOG) accumulates hypoxia inducible factor-l alpha in main pulmonary artery endothelial cells but not in micro pulmonary vessel endothelial cells Adv Exp Med Biol 580: 251-255, 2006 |
| Aizawa H, Aburakawa Y, Suzuki Y, Enomoto H, Makita Y, Kikuchi K, Kimura T Treatment of Japanese restless legs syndrome patients with cabergoline: an open clinical preliminary trial Intern Med 45(7): 453-455, 2006 |
